The researchers used a novel approach to deliver the drug, called a microneedle array, to increase potency.
This array is a fingertip-sized patch of 400 tiny needles that deliver the spike protein pieces into the skin, where the immune reaction is strongest.
The patch goes on like a Band-Aid and then the needles—which are made entirely of sugar and the protein pieces—dissolve into the skin.
“We developed this to build on the original scratch method used to deliver the smallpox vaccine to the skin, but as a high-tech version that is more efficient and reproducible patient to patient,” Falo said. “And it’s actually pretty painless—it feels kind of like Velcro.”
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Credit & Image: Genetic Engineering & Biotechnology News