Long before the COVID-19 pandemic put a spotlight on supply-chain security and drug shortages, the pharmaceutical industry was working on advanced manufacturing technologies that could address supply challenges by increasing manufacturing flexibility and efficiency.
Continuous manufacturing, for example, allows drug manufacturers to more easily adapt supply to demand, incorporate more automation, and have tighter control of quality.
Continuous processes with smaller footprints provide mobility, creating the potential for distributed manufacturing—even bringing drug production to the point of care.
The call for reshoring manufacturing—coming perhaps most loudly from the United States but also a concern in other countries—may be answered in part by using these advanced technologies to produce APIs or to continuously manufacture drug products end-to-end, beginning with basic raw materials and ending with a finished drug form.
External Link: https://www.pharmtech.com/view/advanced-manufacturing-technologies-shift-outside-the-box
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